Staff Profile

Professor of Systems Biology

Don Kulasiri

BSc (Hons) (Eng) MS PhD (Virginia Tech)

Don Kulasiri

Contact Details

Faculty of Agriculture and Life Sciences

Location RFH 066
Phone 64 3 325 2811
Extension
Email Don.Kulasiri@lincoln.ac.nz
 

Currently Teaching

  • COMP308 Computer Modelling and Simulation
  • QMET610 Computational Molecular Systems Biology; Stochastic Processes
  • BICH326 Protein Biochemistry
  • BICH634 Plant Cell Physiology
  • BICH638 Bioinformatics
 

Academic and Professional Background

Founding member and Head of Centre for Advanced Computational Solutions (C-fACS); Visiting Professor, Integrated Systems Biology Cente/Centre for Mathematical Biology, University of Oxford, UK (Jan - June, 2008, Nov 2010) Visiting Fellow, Princeton University, New Jersey (Jan-June, 2004; July 2006) Visiting Professor to Institute of Scientific Computing, Technical University of Braunschweig, Germany (since 2001); Visiting Scholar, Stanford University (Jan-June, 1998); A visiting member of the Centre for Mathematical Biology, Oxford University; a member of Modelling and Simulation Society of Australia and New Zealand, and Sigma Xi honour society; A Panel member of Mathematics, Information Science and Technology (MIST) panel for the PBRF 2012 quality evaluations, Govt  of New Zealand.

 

Current Research and Publications / Selected Publications

  • Molecular Systems Biology
  • Stochastic modelling of biological and environmental systems
  • Bio-Engineering (biotechnology)


Books/Proceedings
Kulasiri, Don, and Verwoerd, Wynand. 2002. Stochastic Dynamics: Modeling solute transport in porous media.  North Holland Applied Mathematics and Mechanics Series . Elsevier Science, Amsterdam. Volume 44. 256 pages.
 
Kulasiri, G. (2011). Computational Modelling of Multi-Scale Non-Fickian Dispersion in Porous Media: An Approach Based on Stochastic Calculus. InTech Publishers, Europe. 237 pages. ISBN 978-953-307-726-0
http://www.intechopen.com/books/computational-modelling-of-multi-scale-solute-dispersion-in-porous-media-an-approach-based-on-stochastic-calculus
 
Les Oxley and Don Kulasiri (editors) Proceedings of the International Congress of Modelling and Simulation, Modelling and Simulation Society of Australia and New Zealand (MSSANZ), December, Christchurch, 2007. 3104 pages.
 
 
Research Articles
Don Kulasiri, Hong Ling and Sandhya Samarasinghe. 2012. A generalised stochastic solute transport model for Multiscale dispersion in porous media. Journal of Porous Media. 15(2):153-170.
 
Lan K. Nguyen and Don Kulasiri. 2011. Distinct Noise-controlling Roles of Multiple Negative Feedback Mechanisms in a Prokaryotic Operon System. IET Systems Biology , Vol. 5, Iss. 2, pp. 145–156.
 
Don Kulasiri. 2010. Computing Molecular Fluctuations in Biochemical Reaction Systems Based on a Mechanistic, Statistical Theory of Irreversible Processes. In
Michael Johnson editor: Methods in Enzymology, Vol. 487,Burlington: Academic Press, Chapter 9, pp. 253-278.
 
Ling, H. , Kulasiri, D. and Samarasinghe S. 2010. Robustness of G1/S checkpoint pathway in cell cycle regulation based on the probability of DNA-damaged cells passing as healthy cells.  BioSystems . 101: 213–221
 
Xie Z, Kulasiri G D, Samarasinghe S, Qian J. 2010. An unbiased sensitivity analysis reveals important parameters controlling periodicity of circadian clock. Biotechnology and Bioengineering, 105: (2) : February: 250-259.
 
Cominetti, O., Matzavinos, A., Samarasinghe, S., Kulasiri, D. Maini, P. and Radek Erban. 2010. DifFUZZY: A fuzzy spectral clustering algorithm for complex data sets. International Journal of Computational Intelligence in Bioinformatics and Systems Biology Vol. 1, No. 4, 2010
 
Rains, G., Kulasiri, D., Zhou, Z., Samarasinghe, S. Tomberlin, J.K. and Olson, D.M. 2009.  Synthesizing Neurophysiology, Genetics, Behaviour and Learning to Produce Whole-Insect Programmable Sensors to Detect Volatile Chemicals. Biotechnology and Genetic Engineering Reviews. Vol. 26. 191-216
 
Lan K. Nguyen, Don Kulasiri. 2009. On the functional diversity of dynamical behaviour in genetic and metabolic feedback systems. BMC Systems Biology  3 (51) May pp: 1-30.
 

Page last updated on: 06/03/2012